Paget’s bone disease: polyostotic presentation in a patient with cancer of the uterine cervix

Authors

  • Héctor Bojórquez-Castillo Universidad Nacional Mayor de San Marcos
  • María de Lourdes Trujillo-Aguirre Hospital Nacional Edgardo Rebagliati Martins- EsSalud
  • Anita Tarco-Virto Hospital EsSalud Edgardo Rebagliati Martins
  • José Luis Paz-Ibarra Hospital EsSalud Edgardo Rebagliati Martins

DOI:

https://doi.org/10.36393/spmi.v32i1.17

Keywords:

Alkaline phosphatase, Paget's bone disease, bone pain, bisphosphonates

Abstract

A 65-year-old female patient with a history of malignant cervical neoplasia and trigeminal neuralgia presents a two-year history of intermittent chronic pain in the lumbar region and left hip. On the outpatient follow-up, a radiographic study of the hip showed a sclerous bone lesion in the left iliac wing and an alkaline phosphatase activity of 225 U/L, suggestive of Paget's disease of the bone. She was hospitalized for study by bone biopsy because of the possibility of bone metastasis. The bone survey, total body multi-slice spiral CT and bone scintigraphy showed similar lesions in right lower jaw and spine. Bisphosphonates was administered with significantly improving of bone and facial pain.

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Published

2019-07-01

Issue

Section

Case report

How to Cite

Paget’s bone disease: polyostotic presentation in a patient with cancer of the uterine cervix. (2019). Revista De La Sociedad Peruana De Medicina Interna, 32(1), 23-26. https://doi.org/10.36393/spmi.v32i1.17