Nasal involvement of extranodal Rosai-Dorfman disease

Authors

  • Rolig Aliaga Hospital Nacional Arzobispo Loayza, Lima
  • José Salinas Hospital Nacional Arzobispo Loayza, Lima
  • Diego Cabezas Hospital Nacional Arzobispo Loayza, Lima
  • Jaime Montes Nacional de Enfermedades Neoplásicas, Lima
  • Pedro Ciudad Hospital Nacional Arzobispo Loayza, Lima
  • Carlos Orrego Hospital Nacional Arzobispo Loayza, Lima
  • Julio Grados Hospital Nacional Arzobispo Loayza, Lima
  • Juan Carlos Samamé Hospital Nacional Arzobispo Loayza, Lima
  • Fiorella Pando Hospital Nacional Arzobispo Loayza, Lima
  • Yinno Custodio Hospital Nacional Arzobispo Loayza, Lima
  • Lidia Aceituno Hospital Nacional Arzobispo Loayza, Lima
  • Gisell Fernández Hospital Nacional Arzobispo Loayza, Lima
  • Dirce Urbina Hospital Nacional Arzobispo Loayza, Lima

DOI:

https://doi.org/10.36393/spmi.v32i4.496

Keywords:

Rosai-Dorfman disease, sinus histiocytosis, extranodal, nasal involvement, emperipolesis, metronomic chemotherapy, immunomodulatory therapy

Abstract

A 60-year-old male patient with recurrent epistaxis, nasal obstruction, oral breathing, endonasal pain, intermittent frontal headache and progressive nasal deformity for four years. Histopathology revealed a chronic inflammatory infiltrate with abundant histiocytes that present the phenomenon of emperipolesis; and, immunohistochemistry confirmed the diagnosis of extranodal Rosai-Dorfman disease. The patient received metronomic chemotherapy and immunomodulatory therapy, a good clinical response was observed after three cycles of treatment.

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Published

2020-02-09

Issue

Vol. 32 No. 4 (2019)

Section

Case report

How to Cite

Nasal involvement of extranodal Rosai-Dorfman disease. (2020). Revista De La Sociedad Peruana De Medicina Interna, 32(4), 148-151. https://doi.org/10.36393/spmi.v32i4.496

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